Anavar (Oxandrolone)

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Anavar (Oxandrolone) is a popular oral anabolic steroid.  Although mild, and considered by many bodybuilders as a weak steroid, it is quite misunderstood in the fitness community.  In this article, I will show you how to best utilize this compound for maximum results.

Chapter 1. Development

In the 1960’s, Anavar (Oxandrolone) was chemically produced by the drug company Pfizer, which has become one of the biggest pharmaceuticals in the world.  The goal was to create something to help hold muscle if a patient was suffering from a wasting disease.  By the late 80’s, Savient pharmaceuticals trademarked the steroid and named it oxandrin and it was FDA approved for hepatitis and Turner syndrome. In the modern era, those with autoimmune problems like AIDS can benefit from its use and it is available by prescription in the United States, although rarely prescribed due to advancements in other drugs.

Chapter 2. Post golden age bodybuilding

It is unclear who came up with the idea for bodybuilders and fitness athletes to use Anavar (Oxandrolone) to use for performance enhancement, but during the 1980’s it started to build a nice reputation thanks to its dry properties.  Remember that during this era aromatase inhibitors did not exist, so bodybuilders were always searching for a steroid that would produce results without the estrogenic risks. 

Chapter 3. Paper ratio

I am always hesitant to talk about anabolic to androgenic ratio’s due to them not being always transferable to the real world.   Anavar (Oxandrolone) on paper has a strong 425 anabolic to low 20 androgenic ratio.  Compare this to Testosterone which is 100 to 100.

In a real-world sense we can expect it to provide an anabolic kick with very little androgenic activity, making it mild enough for females to use.

Chapter 4. The science behind the steroid

Anavar (Oxandrolone) is one of several Dihydrotestosterone (DHT) derivative steroids.  It has an extra atom which replaces the carbon2 within the a-ring.  This prevents metabolic breakdown and also boosts anabolic activity.  The end result in medicine is a good muscle wasting drug, and in the fitness world hard and dry results.

It also is a 17 alpha-alkylated steroid, meaning it has a methyl group attached to prevent the liver from destroying it.  The flip side is this makes it liver toxic, although much less than other oral steroids like superdrol or halotestin for example.

Scientists also noticed that it helps decrease glucocorticoids like cortisol, which eat away at muscle mass especially during stress or disease.  And finally, just like all anabolic steroids, you can expect a boost in nitrogen retention in the muscles, making it easier to build lean muscle mass and harder to lose it back.

anavar results: before and after

Muscle protein FSR. Muscle protein FSR in five young men during the postabsorptive state both before (control, open bar) and after (OX, black bar) OX administration. *, Five days of OX administration increased the synthesis rate of muscle proteins by approximately 44% (P < 0.05). – [JCEM]

Chapter 5. Can it burn fat?

This theory is popular on forums and is a bit misleading.  I will say that no steroid can burn fat, but Anavar (Oxandrolone) gives the impression of fat burn due to 2 things:

  1. It does not aromatize into estrogen so your gains are dry and
  2. It may help your thyroid speed up due to reducing thyroid binding globulin.

At the end of the day just hopping on this steroid will NOT burn fat though, only proper diet can do this.  However, Anavar (Oxandrolone) is great to use while in a deficit to prevent muscle loss when dieting down hard.

Chapter 6. DHT and SHBG

As mentioned earlier Anavar (Oxandrolone) is most certainly a DHT (dihydrotestosterone) derivative.  This means it will not convert to estrogen in the body so you will not experience gynecomastia, water retention, bloat, high blood pressure, or any other estrogenic problems.  The downside is that increases in DHT (dihydrotestosterone) can cause negative side effects including enlarged prostate, head hair loss, and dry joints.  However, the good news here is that Anavar (Oxandrolone) has been shown to be so mild that those negative sides are not pronounced compared to other steroids in a similar class.

Another awesome trait of Anavar (Oxandrolone) is its ability to bind with SHBG (sex hormone binding globulin).  This means it will cause a rise in free testosterone ratio, making the other steroids you are using work better.

Chapter 7. Dosing

We hear a lot of bodybuilders say that Anavar (Oxandrolone) ‘is a waste’ or that ‘it is weak’.  So they will ramp up the dosage to ‘see results’.  This is a complete misunderstanding of the steroid and this mentality needs to be corrected.  Remember since it does not aromatize into estrogen you will not see muscles fill up with water, or the weight scale move up 10 or 15 pounds.  If this is your goal then you shouldn’t use it in the first place.

For those who want good clean gains, they should run it 30mg-60mgs per day.  Female dosages range from 5mg-15mgs a day.

Length of your cycle on Anavar (Oxandrolone) should be 4-8 weeks, with close attention being made to blood work to check the liver health at the 7-week mark.

Chapter 8. Half-life and detection

Anavar (Oxandrolone) half life is about 8-10 hours.  A dosage of 1-2X per day will work just fine.  The detection time is about 3 weeks which is pretty good for those who might be tested down the line.

Chapter 9. Side effects

Anavar (Oxandrolone) is mild, but it should still be respected.  Some broscience claims that it isn’t suppressive, which is dangerous information.  Remember it is still a hormone, so you should expect to have your pituitary shutdown, albeit less so than other steroids while on it, so a full post cycle therapy is always recommended.

As mentioned earlier it is liver toxic, so you need to run liver support such as N2guard while using it and avoid other drugs or alcohol.

One of the biggest complaints with Anavar (Oxandrolone) is the muscle pumps that it will give you.  Although pumps are not a bad thing, they can become a nuisance for those who like to do cardio or who like to do high repetitions in the gym.  Back pumps can become brutal in both situations so supplementing with taurine (included in N2guard) is a wise choice.

Chapter 10. Stacking and results to expect

There is no black and white answer to the age-old question “How much will I gain?”  However, I can provide you some tips on how to use Anavar (Oxandrolone) based on your particular goal.

Section 1. Powerlifters:

I recommend using 50mgs per day along with 250mgs a week Trenbolone.  I have personally hit personal records on all my lifts on this very simple stack.

Section 2. Recomping:

40-60mgs per day with 150mgs per day Testosterone and 500mgs a week Primobolan can provide lean muscle mass gains and a loss in body fat while in a deficit.

Section 3. Bodybuilding:

Those who bodybuild can add 40-60mgs per day into any stack of their choosing to boost their muscle gains while not adding very much side effects.

Section 4. Females:

I recommend using 5-15mgs per day with SARMS (selective androgen receptor modulators) 10mgs LGD (anabolicum/ligandrol) and/or 20mgs Cardarine (GW501516).  You will experience good clean muscle gains along with fat loss.

Chapter 11. Cost and availability

Anavar (Oxandrolone) is one of the most expensive and hard to find oral steroids.  A 6 week run of the steroid can cost you easily in the hundreds of dollars.  For these reasons, it is heavily faked.  You must make sure you do a lot of homework to find a reliable source, check out forums at evolutionary.org to find an approved source.

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